Solution : https://service.sap.com/sap/support/notes/300252 (SAP Service marketplace login required)
Key words : 
missing input parameter values, system generated error message, additional key words rounding, incorrect purchase order item, purchase order item, purchase order quantity, purchase order unit, calling fm md_single_rounding, attached program change, purchase order
Related Notes : 
       
| 316707 | ME21N/ME22N:Rounding values not taken into account | 
| 301105 | Unwanted rounding to rounding value (ME386) | 
| 210114 | ME21N/ME22N: implementation of rounding function |